Antifungal activity of extracts from medicinal plants used by First Nations Peoples of eastern Canada
Antifungal activity of extracts from medicinal plants used by First Nations Peoples of eastern Canada
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DOI：
10.1016/s0378-8741(00)00306-8
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发表时间：
2000-11-01
影响因子：
5.4
通讯作者：
Smith, ML
中科院分区：
文献类型：
--
作者：
Jones, NP;Arnason, JT;Smith, ML
从文献中描述了加拿大东部第一民族的药用植物，选择了18种加拿大东部的植物，并测试了它们的抗真菌活性。为了进行比较，还对随机选择的八种热带植物进行了测试。获得四组植物：常用抗菌剂（n = 6），常用非抗菌剂（n = 6），随机温带（n = 6）和随机热带（n = 8）。这些植物的提取物在圆盘试验中作为六种已知的机会性人类病原体真菌（酿酒酵母菌、新型隐球菌、白色念珠菌、烟曲霉、石膏小孢子菌和毛霉）的生长抑制剂进行了测试。在测试的四种植物组中，基于总体抗真菌活性和抑制真菌种类的数量，流行抗菌药物组的提取物在抑制真菌生长方面明显更有效。(C) 2000爱思唯尔科学爱尔兰有限公司版权所有。
From literature describing medicinal usage of plants by First Nations Peoples in eastern Canada, 18 eastern Canadian plants were selected and tested for their antifungal activities. Eight randomly selected tropical plants were also tested for comparative purposes. Four groups of plants were obtained: popular antimicrobial-remedy (n = 6), popular non-antimicrobial-remedy (n = 6), random temperate (n = 6) and random tropical (n = 8). Extracts from these plants were tested in disk assays as growth inhibitors of six fungi known to be opportunistic human pathogens (Saccharomyces cerevisiae, Cryptococcus neoformans, Candida albicans, Aspergillus fumigatus, Microsporum gypseum and Trichophyton mentagrophytes). Of the four plant groups tested, extracts from the popular antimicrobial-remedy group were significantly more effective at inhibiting fungal growth based on both overall antifungal activity and number of fungal species inhibited. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.