Physical fitness and 6.5-year mortality in an 85-year-old community-dwelling population
Physical fitness and 6.5-year mortality in an 85-year-old community-dwelling population
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DOI：
10.1016/j.archger.2011.04.014
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发表时间：
2012-01-01
影响因子：
4
通讯作者：
Nishihara, Tatsuji
中科院分区：
文献类型：
--
作者：
Takata, Yutaka;Ansai, Toshihiro;Nishihara, Tatsuji
虽然已知身体健康不良与成年人和老年人死亡率增加有关，但这种联系在非常老年人中并不确定。本研究的目的是评估一个非常古老的社区居住人口的协会。参与者（90名男性，117名女性）是居住在日本福冈的85岁个体。2003年进行了基线检查，包括握力和腿伸展的肌肉力量、单腿站立、腿步进率和步行，并对这些受试者进行了6.5年的随访。在随访期间，81人（49名男性和32名女性）死亡。85岁时，幸存者的握力和腿部伸展力量比非幸存者更强。单手或双手的握力每增加1公斤，经性别和血清总胆固醇水平调整后的总死亡率下降5-6%。总死亡率也下降了2%，增加1公斤的腿伸展力量的双腿。调整性别和总胆固醇后，与非参与者相比，步行测试参与者的死亡率下降了57%，步进率测试参与者的死亡率下降了45%。死亡率与参与握力测试、腿伸展力量测试或单腿站立时间测试之间没有发现关联。总之，在非常年长的人群中，不仅握力或腿伸展的肌肉力量差，而且不参加步行试验或腿步进试验是总死亡率的独立预测因素。(C)2011爱思唯尔爱尔兰有限公司保留所有权利。
Although poor physical fitness is known to be associated with increased mortality in adult and elderly populations, this association is not conclusive in very elderly. The purpose of the present study was to evaluate the association for a very old community-dwelling population. The participants (90 males, 117 females) were 85-year-old individuals residing in Fukuoka, Japan. Baseline examinations including muscle strength of the handgrip and leg extension, one-leg standing, leg stepping rate, and walking were performed in 2003 and these subjects were followed for 6.5 years. During the follow-up period, 81 individuals (49 males and 32 females) died. Handgrip strength and leg extension strength at age 85 were stronger in surviving men than in non-survivors. Total mortality adjusted for both gender and serum level of total cholesterol fell 5-6% with a 1-kg increase in the handgrip strength of a single hand or both hands. Total mortality also decreased 2% with a 1 kg increase in the leg extension strength of both legs. With adjustment for gender and total cholesterol, mortality fell by 57% in participants of the walking test and fell by 45% in participants of the stepping-rate test compared to mortality in nonparticipants. No association was found between mortality and participation in the handgrip strength test, leg extension strength test, or one-leg standing time test. In conclusion, not only poor muscle strength in handgrip or leg extension, but also nonparticipation in walking test or leg-stepping test were independent predictors of total mortality in a very elderly population. (C) 2011 Elsevier Ireland Ltd. All rights reserved.