INTRAUTERINE GROWTH-RETARDATION AND PRETERM DELIVERY

INTRAUTERINE GROWTH-RETARDATION AND PRETERM DELIVERY
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DOI:
10.1016/0002-9378(93)90681-8
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发表时间:
1993-06-01
影响因子:
9.8
通讯作者:
OTT, WJ
OTT, WJ
中科院分区:
医学1区
文献类型:
--
作者:
OTT, WJ

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目的:我们进行了一项回顾性研究,以确定早产儿是否比足月儿有更高的宫内发育迟缓发生率。如果早产与宫内生长迟缓显着相关,然后定义宫内生长迟缓与特定人群的出生后出生体重的胎龄曲线将低估早产儿的发病率。研究设计:1990年的数据被用来构建一个出生后出生体重的胎龄曲线。然后用该曲线分析1991年出生体重数据,并确定妊娠各周宫内生长迟缓(<第10百分位数)的发生率。根据额外的出生后出生体重胎龄曲线和两个产前超声估计的胎儿体重胎龄曲线,婴儿也被归类为宫内发育迟缓。对1991年分娩数据的分析表明,两种超声曲线均显示随着孕周的增加,胎儿宫内发育迟缓的发生率显著降低,结论:本研究结果支持了以往的研究结果,即胎儿宫内发育迟缓在早产儿中比在足月儿中更常见,并与胎儿宫内发育迟缓与早产显著相关的假说相一致。
OBJECTIVE: A retrospective study was undertaken to determine if premature infants had a higher incidence of intrauterine growth retardation than term infants did. If premature labor is significantly associated with intrauterine growth retardation, then defining intrauterine growth retardation with a population-specific postnatal birth weight for gestational age curve would underestimate the incidence in preterm infants.STUDY DESIGN: Data for the year 1990 were used to construct a postnatal birth weight for gestational-age curve. This curve was then used to analyze 1991 birth weight data and to determine the incidence of intrauterine growth retardation (< 10th percentile) at each week of gestation. Infants were also classified as having intrauterine growth retardation on the basis of an additional postnatal birth weight for gestational-age curve and two antenatal ultrasonic estimated fetal-weight-for-gestational-age curves.RESULTS: Analysis of the 1991 delivery data indicated that both ultrasonography curves showed a significant decrease in the incidence of intrauterine growth retardation with advancing gestational age, whereas the postnatal curves did not.CONCLUSION: The results give full support to previous reports that suggest intrauterine growth retardation is more common in preterm than in term infants and are consistent with the hypothesis that intrauterine growth retardation is significantly related to premature birth.