Effects of Storage Time on Quantitative and Qualitative Platelet Function after Transfusion
Effects of Storage Time on Quantitative and Qualitative Platelet Function after Transfusion
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DOI：
10.1097/00132586-199610000-00021
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发表时间：
1995-12
期刊：
影响因子：
8.8
通讯作者：
B. Rosenfeld;Barbara M Herfel;N. Faraday;A. Fuller;H. Braine
中科院分区：
文献类型：
--
作者：
B. Rosenfeld;Barbara M Herfel;N. Faraday;A. Fuller;H. Braine
血小板减少症患者在手术和侵入性操作前越来越多地使用血小板输注来改善止血功能。然而，关于输血后立即定量和定性血小板应答的数据有限。一些作者认为，输注的血小板需要时间在体内恢复最大功能，这取决于血小板储存的持续时间。因此，手术和侵入性操作的时机可能不会出现最佳血小板功能。
Background Platelet transfusions are being used increasingly in patients with thrombocytopenia to improve hemostatic function before surgery and invasive procedures. However, there are limited data on the immediate quantitative and qualitative platelet response after transfusion. Some authors have suggested that transfused platelets require time in vivo to regain maximal function, which is dependent on the duration of platelet storage. Therefore, the timing of surgery and invasive procedures with optimal platelet function may not be occurring.