Typical female 2nd-4th finger length (2D:4D) ratios in male-to-female transsexuals -: possible implications for prenatal androgen exposure
Typical female 2nd-4th finger length (2D:4D) ratios in male-to-female transsexuals -: possible implications for prenatal androgen exposure
复制标题
DOI：
10.1016/j.psyneuen.2005.07.005
复制
发表时间：
2006-02-01
影响因子：
3.7
通讯作者：
Stalla, GK
中科院分区：
文献类型：
--
作者：
Schneider, HJ;Pickel, J;Stalla, GK
产前暴露于雄激素已被牵连在易性癖，但病因的条件仍然不清楚。第2至第4（2D：4D）指长的比例已被认为是负相关的产前雄激素暴露。我们想评估变性欲者和对照组在2D：4D比例上的差异，研究包括63名男性变性欲者（MFT），43名女性变性欲者（FMT），65名女性变性欲者和58名配偶变性欲者。所有人的手掌和手指都被复印了。右利手个体之间的比较显示，MFT中的右手2D：4D高于对照配偶，但与对照雌性中观察到的相似。在FMT中，我们发现2D：4D相对于对照雌性无差异。我们的研究结果支持男变女易性癖的生物学病因学，提示MFT患者产前雄激素暴露减少。我们没有发现产前激素暴露在女变男变性中的作用。(c)2005爱思唯尔有限公司保留所有权利。
Prenatal exposure to androgens has been implicated in transsexualism but the etiology of the condition remains unclear. The ratio of the 2nd to the 4th (2D:4D) digit lengths has been suggested to be negatively correlated to prenatal androgen exposure. We wanted to assess differences in 2D:4D ratio between transsexuals and controls.Sixty-three male-to-female transsexuals (MFT), 43 female-to-mate transsexuals (FMT), and 65 female and 58 mate controls were included in the study. Photocopies of the palms and digits of the hands were taken of all. subjects and 2D:4D ratios were measured, according to standard published procedures.Comparison between right-handed individuals revealed that the right-hand 2D:4D in MFT is higher than in control mates but similar to that observed in control females. In FMT we found no differences in 2D:4D relative to control females. Our findings support a biological etiology of male-to-female transsexualism, implicating decreased prenatal androgen exposure in MFT. We have found no indication of a role of prenatal hormone exposure in female-to-male transsexualism. (c) 2005 Elsevier Ltd. All rights reserved.