EB virus-specific IgA in serum of patients with infectious mononucleosis and of healthy people of different ages.
EB virus-specific IgA in serum of patients with infectious mononucleosis and of healthy people of different ages.
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传染性单核细胞增多症患者和不同年龄健康人血清中的 EB 病毒特异性 IgA。
DOI：
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发表时间：
1979
影响因子：
3.4
通讯作者：
M. Woodroof
中科院分区：
文献类型：
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作者：
J. Edwards;M. Woodroof
对以下血清进行了EB病毒特异性伊加检测：来自61例传染性单核细胞增多症（IM）患者和195名EB病毒IgG阳性健康学生的系列血清;来自1469名不同年龄的人、63例未经治疗的霍奇金病患者和22名新生儿的单一血清。EB病毒特异性伊加在88%的IM患者、18.5%的EB病毒IgG阳性的健康学生和13.5%的同一学生3年后的重复样本中检出。2 ~ 70岁EBVIgG阳性者单次血清中伊加的检出率在5 ~ 30%之间。较高的百分比发生在最近血清转换率较高的年龄组。15%的霍奇金病患者血清中EBV伊加呈阳性，其发病率与25-45岁年龄组的健康成人相似。EBVIgG阳性的新生儿血清均未出现伊加阳性反应。
The following sera were tested for EB virus-specific IgA: serial sera from 61 cases of infectious mononucleosis (IM) and from 195 EBV IgG positive healthy students; single sera from each of 1469 persons of different ages, 63 cases of untreated Hodgkin's disease, and 22 neonates. EBV specific IgA was found in the sera from 88% of cases of IM, from 18.5% of EBV IgG positive healthy students, and in 13.5% of repeat samples from the same students three years later. The incidence of EBV IgA varied from 5 to 30% at different ages in single sera from EBV IgG positive persons aged 2 to 70 years. The higher percentages occurred in the age groups where recent sero-conversion rates were high. Fifteen percent of sera from cases of Hodgkin's disease were positive for EBV IgA, an incidence similar to that for healthy adults in the age group 25-45 years. None of the EBV IgG positive sera from neonates gave a positive reaction for EBV IGA.