STRUCTURAL AND IMMUNOCHEMICAL STUDIES OF TEICHOIC-ACID OF LISTERIA-MONOCYTOGENES
STRUCTURAL AND IMMUNOCHEMICAL STUDIES OF TEICHOIC-ACID OF LISTERIA-MONOCYTOGENES
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DOI：
10.1093/oxfordjournals.jbchem.a134275
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发表时间：
1983-01-01
影响因子：
2.7
通讯作者：
AZUMA, I
中科院分区：
文献类型：
--
作者：
KAMISANGO, K;FUJII, H;AZUMA, I
从乳杆菌细胞壁中分离得到一种具有免疫活性的磷壁酸成分。单核细胞增生菌株EGD。磷壁酸组分，占约10%。细胞壁重量的20%含有N-乙酰葡糖胺、鼠李糖、核糖醇和P，M比为0.95：1.0：0.97：0.98。磷壁酸链的MW为约120，000，通过凝胶过滤分析。根据磷壁酸的甲基化分析、Smith降解和PMR光谱分析的结果，以及通过氢氟酸处理获得的片段的表征，推断可能的结构。
An immunologically active teichoic acid component was isolated from the cell wall of L. monocytogenes strain EGD. The teichoic acid component, accounting for .apprx. 20% of the weight of cell wall, contained N-acetylglucosamine, rhamnose, ribitol and P in a M ration of 0.95:1.0:0.97:0.98. The MW of the teichoic acid chain was .apprx. 120,000, as analyzed by gel filtration. The probable structure was deduced from the results of methylation analysis, Smith degradation and PMR spectrometry of the teichoic acid, together with the characterization of fragments obtained by treatment with hydrofluoric acid.