Risk of severe COVID-19 from the Delta and Omicron variants in relation to vaccination status, sex, age and comorbidities - surveillance results from southern Sweden, July 2021 to January 2022.
Risk of severe COVID-19 from the Delta and Omicron variants in relation to vaccination status, sex, age and comorbidities - surveillance results from southern Sweden, July 2021 to January 2022.
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DOI：
10.2807/1560-7917.es.2022.27.9.2200121
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发表时间：
2022-03
期刊：
影响因子：
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通讯作者：
Björk J
中科院分区：
文献类型：
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作者：
Kahn F;Bonander C;Moghaddassi M;Rasmussen M;Malmqvist U;Inghammar M;Björk J
我们比较了2021年和2022年两个时期的严重COVID-19风险，当时Delta和Omicron分别是瑞典斯堪尼亚县的主要病毒变体。我们调整了性别、年龄、合并症、既往感染和疫苗接种的差异。在接种疫苗的病例中，Omicron引起严重疾病的风险明显降低。在未接种疫苗的人群中，这一比例也较低，但在患有两种或两种以上合并症的老年人和中年男性中，这一比例仍然很高（> 5%）。应继续努力提高疫苗接种率。
We compared the risk of severe COVID-19 during two periods 2021 and 2022 when Delta and Omicron, respectively, were the dominating virus variants in Scania county, Sweden. We adjusted for differences in sex, age, comorbidities, prior infection and vaccination. Risk of severe disease from Omicron was markedly lower among vaccinated cases. It was also lower among the unvaccinated but remained high (> 5%) for older people and middle-aged men with two or more comorbidities. Efforts to increase vaccination uptake should continue.