EARLY GROWTH AND DEATH FROM CARDIOVASCULAR-DISEASE IN WOMEN
EARLY GROWTH AND DEATH FROM CARDIOVASCULAR-DISEASE IN WOMEN
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DOI：
10.1136/bmj.307.6918.1519
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发表时间：
1993-12-11
影响因子：
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通讯作者：
SIMMONDS, SJ
中科院分区：
文献类型：
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作者：
OSMOND, C;BARKER, DJP;SIMMONDS, SJ
目的-确定子宫内和婴儿期生长与男性心血管疾病死亡之间的联系是否也存在于女性中。设计-对出生体重和 1 岁时体重已记录的女性和男性进行跟踪研究。地点-英国赫特福德郡。受试者-1911-30 年间出生的 5585 名女性和 10141 名男性。主要结果指标-心血管标准化死亡率 结果 - 在女性和男性中，低出生体重组和高出生体重组之间心血管疾病死亡率逐渐下降（女性的 chi2=4.3，p=0.04，chi2=8.5，p
Objective-To determine whether the link suggested between growth in utero and during infancy and death from cardiovascular disease in men is also present in women.Design-Follow up study of women and men whose birth weight and weight at 1 year of age had been recorded.Setting-Hertfordshire, England.Subjects-5585 women and 10141 men born during 1911-30.Main outcome measures-Standardised mortality ratios for cardiovascular disease.Results-Among women and men death rates from cardiovascular disease fell progressively between the low and high birth weights groups (chi2=4.3, p=0.04 for women, chi2=8.5, p