Pediatric mania: A developmental subtype of bipolar disorder?
Pediatric mania: A developmental subtype of bipolar disorder?
复制标题
DOI：
10.1016/s0006-3223(00)00911-2
复制
发表时间：
2000-09-15
影响因子：
10.6
通讯作者：
Wozniak, J
中科院分区：
文献类型：
--
作者：
Biederman, J;Mick, E;Wozniak, J
尽管一直存在争议，但儿科躁狂症罕见或不存在的观点不仅受到病例报告的挑战，而且受到系统研究的挑战。这项研究有力地表明，儿童躁狂症可能并不罕见，但可能很难诊断。由于躁狂症儿童很可能成为双相情感障碍的成年人，儿童期发作的躁狂症的识别和表征可能有助于确定一个有意义的发展亚型的双相情感障碍值得进一步研究。使小儿躁狂症的诊断复杂化的主要困难包括：1）其合并症模式可能是成人标准所独有的，特别是与注意缺陷/多动障碍、攻击性和行为障碍的重叠; 2）与物质使用障碍的重叠; 3）与创伤和逆境的相关性; 4）其对治疗的反应是成人标准所不典型的。(C)2000年生物精神病学学会。
Despite ongoing controversy, the view that pediatric mania is rare or nonexistent has been increasingly challenged not only by case reports, but also by systematic research. This research strongly suggests that pediatric mania may not be rare but that it may be difficult to diagnose. Since children with mania are likely to become adults with bipolar disorder, the recognition and characterization of childhood-onset mania may help identify a meaningful developmental subtype of bipolar disorder worthy of further investigation. The major difficulties that complicate the diagnosis of pediatric mania include: 1) its pattern of comorbidity may be unique by adult standards, especially its overlap with attention-deficit/hyperactivity disorder, aggression, and conduct disorder; 2) its overlap with substance use disorders; 3) its association with trauma and adversity; and 4) its response to treatment is atypical by adult standards. (C) 2000 Society of Biological Psychiatry.