Delay discounting in schizophrenia.

Delay discounting in schizophrenia.
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DOI:
10.1080/13546800601005900
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发表时间:
2007-05-01
影响因子:
1.7
通讯作者:
Gold, James M
Gold, James M
中科院分区:
医学4区
文献类型:
--
作者:
Heerey, Erin A;Robinson, Benjamin M;Gold, James M

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背景技术背景:众所周知,患有精神分裂症的个体具有多巴胺能异常以及与记忆相关的困难,这两者都与冲动决策有关。我们使用了延迟折扣措施,以测试患者作出面向未来的decisions.METHODS的程度:42例精神分裂症患者和29名健康参与者完成了延迟折扣措施沿着与测试的认知功能,并在患者中,症状ratings.RESULTS:患者折扣更陡比比较参与者。折扣患者之间的记忆能力和负向symptoms.CONCLUSIONS:冲动的决策证明了患者表明,他们可能倾向于选择即时的长期奖励,即使他们的利益是更好地服务于选择后者。改善认知功能可以提高他们做出面向未来的决定的能力。
BACKGROUND: It is well known that individuals with schizophrenia have dopaminergic abnormalities as well as memory-related difficulties, both of which are associated with impulsive decision making. We used a delay discounting measure to test the degree to which patients make future-oriented decisions.METHODS: 42 patients with schizophrenia and 29 healthy participants completed a delay discounting measure along with tests of cognitive function and, in patients, symptom ratings.RESULTS: Patients discounted more steeply than did comparison participants. Discounting among patients related to memory capacity and tended to relate inversely to negative symptoms.CONCLUSIONS: The impulsive decision making evidenced by patients suggests that they may be prone to choosing immediate over long-term rewards, even when their interests are better served by choosing the latter. Improving cognitive function may enhance their ability to make future-oriented decisions.