Color Doppler Ultrasonography Is a Useful Tool for Diagnosis of Peripheral Artery Disease in Type 2 Diabetes Mellitus Patients with Ankle-Brachial Index 0.91 to 1.40.
Color Doppler Ultrasonography Is a Useful Tool for Diagnosis of Peripheral Artery Disease in Type 2 Diabetes Mellitus Patients with Ankle-Brachial Index 0.91 to 1.40.
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彩色多普勒超声对踝臂指数0.91 ~ 1.40的2型糖尿病患者外周动脉病变的诊断价值
DOI：
10.4093/dmj.2018.42.1.63
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发表时间：
2018-03
影响因子：
5.9
通讯作者：
Choi SH
中科院分区：
文献类型：
--
作者：
Hur KY;Jun JE;Choi YJ;Lee YH;Kim DJ;Park SW;Huh BW;Lee EJ;Jee SH;Huh KB;Choi SH
踝肱指数（ABI）在血管不太严重或钙化的受试者中的临床应用尚不清楚。因此，我们研究了彩色多普勒超声对2型糖尿病（T2DM）患者外周动脉疾病（PAD）的诊断价值。我们分析了2003年至2006年期间同时接受ABI、颈动脉内膜-中膜厚度（CIMT）测量和彩色多普勒超声检查的324例T2DM患者。根据Jager标准确定PAD患者的狭窄程度，彩色多普勒超声将PAD定义为III级（50% ~ 99%狭窄）或IV级（100%狭窄）。采用Logistic回归分析和受试者工作特征曲线分析评价ABI为0.91 ~ 1.40的患者发生PAD的危险因素。324例患者中，77例（23.8%）ABI为0.91 ~ 1.40，但诊断为PAD。彩色多普勒超声检查显示，与ABI≤0.90的PAD患者相比，ABI为0.91 ~ 1.40的PAD患者出现膝上动脉狭窄、双侧病变和多血管受累的情况较少。多因素logistic回归分析显示，在调整常规危险因素后，年龄较大、吸烟状况、腿部症状的存在和高CIMT与ABI患者的PAD存在显著相关（0.91 ~ 1.40）。CIMT在ABI患者中预测PAD存在的能力为0.91 ~ 1.40。对于ABI为0.91 ~ 1.40，但CIMT较高的T2DM患者，彩色多普勒超声是检测PAD的有效工具。
The clinical utility of ankle-brachial index (ABI) is not clear in subjects with less severe or calcified vessel. Therefore, we investigated the usefulness of color Doppler ultrasonography for diagnosing peripheral artery disease (PAD) in type 2 diabetes mellitus (T2DM) subjects. We analyzed 324 T2DM patients who concurrently underwent ABI and carotid intima-media thickness (CIMT) measurements and color Doppler ultrasonography from 2003 to 2006. The degree of stenosis in patients with PAD was determined according to Jager's criteria, and PAD was defined as grade III (50% to 99% stenosis) or IV stenosis (100% stenosis) by color Doppler ultrasonography. Logistic regression analysis and receiver operating characteristic curve analysis were performed to evaluate the risk factors for PAD in patients with ABI 0.91 to 1.40. Among the 324 patients, 77 (23.8%) had ABI 0.91 to 1.40 but were diagnosed with PAD. Color Doppler ultrasonography demonstrated that suprapopliteal arterial stenosis, bilateral lesions, and multivessel involvement were less common in PAD patients with ABI 0.91 to 1.40 than in those with ABI ≤0.90. A multivariate logistic regression analysis demonstrated that older age, current smoking status, presence of leg symptoms, and high CIMT were significantly associated with the presence of PAD in patients with ABI 0.91 to 1.40 after adjusting for conventional risk factors. CIMT showed significant power in predicting the presence of PAD in patients with ABI 0.91 to 1.40. Color Doppler ultrasonography is a useful tool for the detection of PAD in T2DM patients with ABI 0.91 to 1.40 but a high CIMT.
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影响因子：
37.8
作者：
Gerhard-Herman MD;Gornik HL;Barrett C;Barshes NR;Corriere MA;Drachman DE;Fleisher LA;Fowkes FG;Hamburg NM;Kinlay S;Lookstein R;Misra S;Mureebe L;Olin JW;Patel RA;Regensteiner JG;Schanzer A;Shishehbor MH;Stewart KJ;Treat-Jacobson D;Walsh ME
通讯作者：
Walsh ME
影响因子：
5.3
作者：
Park, Seok Won;Kim, Soo Kyung;Huh, Kap Bum
通讯作者：
Huh, Kap Bum
影响因子：
8.9
作者：
Olin, Jeffrey W.;Sealove, Brett A.
通讯作者：
Sealove, Brett A.
影响因子：
16.2
作者：
Gregg, EW;Sorlie, P;Geiss, L
通讯作者：
Geiss, L
影响因子：
120.7
作者：
Bhatt, DL;Steg, PG;Zuzarte, K
通讯作者：
Zuzarte, K