Auditory intensity processing: Effect of MRI background noise
Auditory intensity processing: Effect of MRI background noise
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DOI：
10.1016/j.heares.2016.01.007
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发表时间：
2016-03-01
期刊：
影响因子：
2.8
通讯作者：
Brechmann, Andre
中科院分区：
文献类型：
--
作者：
Angenstein, Nicole;Stadler, Joerg;Brechmann, Andre
对人类主动听觉强度辨别的研究表明，关于加工的偏侧化，结果是模棱两可的。而实验中，一个中等的背景下发现的证据，右侧偏侧处理的强度，功能性磁共振成像（fMRI）的研究与背景扫描仪噪声表明更多的左侧偏侧处理。在本fMRI研究中，我们比较了传统的连续回波平面成像（EPI）序列与响亮的背景扫描仪噪声和快速低角度拍摄（FLASH）序列与软背景扫描仪噪声之间的强度处理的任务依赖性偏侧化。为了确定处理的偏侧化，我们采用了对侧噪声程序。线性调频（FM）音单耳和无对侧噪声。在EPI和FLASH测量过程中，当参与者对FM音调的强度进行分类时，左侧听觉皮层比右侧听觉皮层的参与程度更高。对侧噪声对左侧听觉皮层活动的强烈影响表明了这一点。这意味着背景扫描仪噪声的大幅降低仍然会导致显著的左侧化效应。这表明，反向偏侧化在功能磁共振成像研究与响亮的背景噪声与软背景的研究相比，不能完全解释的MRI背景噪声。(C)© 2016 Elsevier B.V.版权所有。
Studies on active auditory intensity discrimination in humans showed equivocal results regarding the lateralization of processing. Whereas experiments with a moderate background found evidence for right lateralized processing of intensity, functional magnetic resonance imaging (fMRI) studies with background scanner noise suggest more left lateralized processing. With the present fMRI study, we compared the task dependent lateralization of intensity processing between a conventional continuous echo planar imaging (EPI) sequence with a loud background scanner noise and a fast low-angle shot (FLASH) sequence with a soft background scanner noise. To determine the lateralization of the processing, we employed the contralateral noise procedure. Linearly frequency modulated (FM) tones were presented monaurally with and without contralateral noise. During both the EPI and the FLASH measurement, the left auditory cortex was more strongly involved than the right auditory cortex while participants categorized the intensity of FM tones. This was shown by a strong effect of the additional contralateral noise on the activity in the left auditory cortex. This means a massive reduction in background scanner noise still leads to a significant left lateralized effect. This suggests that the reversed lateralization in fMRI studies with loud background noise in contrast to studies with softer background cannot be fully explained by the MRI background noise. (C) 2016 Elsevier B.V. All rights reserved.