Enantioselective aldol reaction of trimethoxysilyl enol ether catalyzed by lithium binaphtholate
Enantioselective aldol reaction of trimethoxysilyl enol ether catalyzed by lithium binaphtholate
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DOI：
10.1021/ol048485
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发表时间：
2004-10-14
期刊：
影响因子：
5.2
通讯作者：
Hashimoto, S
中科院分区：
文献类型：
--
作者：
Nakajima, M;Orito, Y;Hashimoto, S
（图）研究了一种由二萘酸锂催化的三甲氧基硅烯醇醚醛醇反应，其中水作为添加剂，在立体选择性中起关键作用。这是手性碱催化三甲氧基硅烯醇醚醛醇反应的第一个例子。
(GRAPHICS)An aldol reaction of trimethoxysilyl enol ether catalyzed by lithium binaphtholate, in which water serves as an additive and plays a pivotal role in stereoselectivitles, was developed. This is the first example of an aldol reaction of trimethoxysilyl enol ether catalyzed by a chiral base.