Stokes polarimetry imaging of rat tail tissue in a turbid medium: degree of linear polarization image maps using incident linearly polarized light.

Stokes polarimetry imaging of rat tail tissue in a turbid medium: degree of linear polarization image maps using incident linearly polarized light.
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DOI:
10.1117/1.2162851
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发表时间:
2006
影响因子:
3.5
通讯作者:
Paul J. Wu;J. Walsh
Paul J. Wu;J. Walsh
中科院分区:
医学3区
文献类型:
--
作者:
Paul J. Wu;J. Walsh

文献摘要

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用入射线偏振光照射在组织上的照明和发射光的偏振状态测量提供了一种可以区分各种组织结构的方法。鼠尾嵌入浑浊的明胶中,使其上面有不同深度的介质。通过改变照射线偏振光的入射偏振角(IPA)、组织的几何形状和取向角,利用Stokes偏振成像技术创建了一系列二维度的线偏振图像图。图像地图显示了大鼠尾部的极化敏感结构的位置,包括软组织、椎间盘和肌腱。在图像地图中观察到的形态学表明,根据组织类型和下垫层,光的去极化不同的位置。这些数据表明,改变IPA的重要性,以及组织二色性和双折射影响线偏振图像映射的程度。获得有关地下组织结构的诊断信息。
Illumination with incident linearly polarized light on tissue and polarization state measurements of the remitted light provide a means by which various tissue structures can be differentiated. A rat tail is embedded within a turbid gelatin such that there is a variable depth of medium above it. By varying the incident polarization angle (IPA) of the illuminating linearly polarized light, the geometry, and the orientation angle of the tissue, a series of 2-D degree of linear polarization image maps are created using our Stokes polarimetry imaging technique. The image maps show locations of the polarization-sensitive structures in the rat tail, including soft tissue, intervertebral disks, and tendons. The observed morphologies in the image maps indicate locations where the depolarization of light differs according to the tissue type and underlying layers. The data indicate the importance of varying the IPA, and that tissue dichroism and birefringence affect the degree of linear polarization image maps. Diagnostic information regarding subsurface tissue structures is obtained.