Comparison of Baseline Urological Symptoms in Men and Women in the MAPP Research Cohort
Comparison of Baseline Urological Symptoms in Men and Women in the MAPP Research Cohort
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DOI：
10.1016/j.juro.2014.11.016
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发表时间：
2015-05-01
影响因子：
6.6
通讯作者：
Landis, J. Richard
中科院分区：
文献类型：
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作者：
Clemens, J. Quentin;Clauw, Daniel J.;Landis, J. Richard
目的：间质性膀胱炎/膀胱痛综合征的临床特征与慢性前列腺炎/慢性盆腔疼痛综合征相似。然而，据我们所知，还没有研究直接比较这些症状在男性和女性中的特征。材料和方法：MAPP研究网络招募了191名男性和233名女性，患有IC/BPS或CP/CPPS。基线数据包括人口学、间质性膀胱炎症状指数和问题指数得分；泌尿生殖系疼痛指数得分；美国泌尿学会症状指数得分；利克特量表，用于评估尿路紧迫度、频率、疼痛和总体症状严重程度；以及关于最麻烦的盆腔症状的单一问题。结果：在调整年龄、收入和症状持续时间后，疼痛严重程度的测量在性别之间是相似的。女性ICSI、ICPI和AUASI的平均得分显著高于男性，反映了女性更多的膀胱集中症状。男性和女性最烦人的单一症状是耻骨/膀胱区疼痛(男性34%，女性58%)。MAPP队列中的男性和女性的特征与IC/BPS和CP/CPPS的其他研究队列中报道的相似。结论：我们的研究结果表明疼痛严重程度在性别上相似，集中在膀胱的症状(紧迫感、耻骨上疼痛、频率)在女性中更常见。然而，相当大比例的男性也报告了这些类型的膀胱症状。
Purpose: The clinical features of the interstitial cystitis/bladder pain syndrome are similar to those of the chronic prostatitis/chronic pelvic pain syndrome. However, to our knowledge no studies have directly compared the characteristics of these syndromes in men and women.Materials and Methods: The MAPP Research Network recruited 191 men and 233 women with IC/BPS or CP/CPPS. Baseline data included demographics, Interstitial Cystitis Symptom Index and Problem Index scores; Genitourinary Pain Index score; American Urological Association Symptom Index score; Likert scales to assess urinary urgency, frequency, pain and overall symptom severity; and a single question about the most bothersome pelvic symptom.Results: After adjustment for age, income and symptom duration, measures of pain severity were similar across genders. Mean scores for the ICSI, ICPI and AUASI were significantly higher in women than in men, reflecting more bladder focused symptoms in women. The most bothersome single symptom in men as well as in women was pain in the pubic/bladder area (men 34%, women 58%). The characteristics of the men and women in the MAPP cohort were similar to those reported in other research cohorts for IC/BPS and CP/CPPS.Conclusions: Our findings indicate that pain severity is similar for both genders and that bladder focused symptoms (urgency, suprapubic pain, frequency) are more common in women. However, a substantial proportion of men also reported these types of bladder symptoms.