Impact of fluorescein angiographic characteristics of macular lesions on outcomes after macular translocation 360 degree surgery in eyes with age-related macular degeneration.
Impact of fluorescein angiographic characteristics of macular lesions on outcomes after macular translocation 360 degree surgery in eyes with age-related macular degeneration.
复制标题
黄斑病变荧光素血管造影特征对年龄相关性黄斑变性眼黄斑移位 360 度手术后结果的影响。
DOI：
10.1097/00006982-200507000-00010
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发表时间：
2005
期刊：
影响因子：
--
通讯作者：
Toth,CynthiaA
中科院分区：
文献类型：
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作者：
Mruthyunjaya,Prithvi;Stinnett,SandraS;Toth,CynthiaA
目的：评估术前病变大小和组成与黄斑移位手术后1年的视力结果之间的关系，360周边视网膜切除术（MT360）治疗新生血管性年龄相关性黄斑变性（AMD.Methods）：一个前瞻性的，干预性的，连续的，非比较性的病例系列的64例双侧新生血管性AMD与MT360治疗的眼睛，最近的视力丧失。设盲的审查者根据黄斑光凝研究盘区（MPS DA）的病变大小和主要病变组成（典型或隐匿性脉络膜新生血管或视网膜下出血）对术前荧光素血管造影片进行分级。中位变化的距离和近的视力和阅读速度在术后12个月进行了分析，就病变的大小和composition.Results：有小，中型或大型术前病变的结果之间没有显着差异。在每个主要病变组成组的患者有中位数改善视力的结果与显着改善近视力和阅读速度为主的经典和隐匿性lesions.Conclusion：MT360稳定或改善视功能的新生血管性AMD患者的病变大小类别和各种病变组成。切除视网膜下病变和将中央凹重新定位在更健康的视网膜色素上皮床上可能是这些改善的原因。
Purpose:To evaluate the relationship between preoperative lesion size and composition and visual outcomes at 1 year after macular translocation surgery with 360 peripheral retinectomy (MT360) for neovascular age-related macular degeneration (AMD).Methods:A prospective, interventional, consecutive, noncomparative case series of 64 patients with bilateral neovascular AMD treated with MT360 in the eye with more recent vision loss. Masked reviewers graded preoperative fluorescein angiograms for lesion size in Macular Photocoagulation Study disk areas (MPS DAs) and predominant lesion composition (classic or occult choroidal neovascularization or subretinal hemorrhage). Median changes in distance and near visual acuities and reading speed at 12 months after surgery were analyzed with respect to lesion size and composition.Results:There was no significant difference between the outcomes for small-, medium-or large-sized preoperative lesions. Patients in each predominant lesion composition group had median improvement in visual outcomes with significant improvement in near visual acuity and reading speed for predominantly classic and occult lesions.Conclusion:MT360 stabilizes or improves visual function in patients with neovascular AMD irrespective of lesion size categories and with a variety of lesion compositions. Removal of the subretinal lesion and repositioning of the fovea over a healthier retinal pigment epithelial bed may account for these improvements.