Improving the productivity of Candida glycerinogenes in the fermentation of ethanol from non‐detoxified sugarcane bagasse hydrolysate by a hexose transporter mutant

Improving the productivity of Candida glycerinogenes in the fermentation of ethanol from non‐detoxified sugarcane bagasse hydrolysate by a hexose transporter mutant
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DOI:
10.1111/jam.15059
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发表时间:
2021-03
影响因子:
4
通讯作者:
Yanming Qiao;Jianqiao Zhou;Xinyao Lu;H. Zong;B. Zhuge
Yanming Qiao;Jianqiao Zhou;Xinyao Lu;H. Zong;B. Zhuge
中科院分区:
生物学3区
文献类型:
--
作者:
Yanming Qiao;Jianqiao Zhou;Xinyao Lu;H. Zong;B. Zhuge

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在这项研究中,我们试图通过鉴定这种酵母中对葡萄糖消耗有很大贡献的己糖转运蛋白,并通过添加这种转运蛋白的额外拷贝并增强其膜定位稳定性(MLS)来提高产甘油假丝酵母从非脱毒甘蔗渣水解物(NDSBH)中生产乙醇的生产率。
In this study, we attempted to increase the productivity of Candida glycerinogenes yeast for ethanol production from non‐detoxified sugarcane bagasse hydrolysates (NDSBH) by identifying the hexose transporter in this yeast that makes a high contribution to glucose consumption, and by adding additional copies of this transporter and enhancing its membrane localisation stability (MLS).