A selective cyclooxygenase‐2 inhibitor prevents inflammation‐related squamous cell carcinogenesis of the forestomach via duodenogastric reflux in rats

A selective cyclooxygenase‐2 inhibitor prevents inflammation‐related squamous cell carcinogenesis of the forestomach via duodenogastric reflux in rats
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选择性环氧合酶-2抑制剂通过十二指肠胃反流预防炎症相关的前胃鳞状细胞癌变

DOI:
10.1002/cncr.23990
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发表时间:
2009
期刊:
影响因子:
6.2
通讯作者:
T. Hattori
T. Hattori
中科院分区:
医学1区
文献类型:
--
作者:
M. Oba;K. Miwa;T. Fujimura;S. Harada;S. Sasaki;K. Oyama;T. Ohta;T. Hattori

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十二指肠反流在没有任何致癌物的大鼠前胃中引起炎症相关的鳞状细胞癌。本研究的目的是研究选择性环加氧酶(COX)‐2抑制剂美洛昔康在预防这种癌变中的作用。
Duodenal reflux causes inflammation‐related squamous cell carcinogenesis in the forestomach of rats without any carcinogens. The aim of this study was to investigate the efficacy of a selective cyclooxygenase (COX)‐2 inhibitor, meloxicam, in preventing this carcinogenesis.
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