USE OF ULTRASOUND TO MONITOR PRENATAL GROWTH AND DEVELOPMENT IN THE COMMON MARMOSET (CALLITHRIX-JACCHUS)
USE OF ULTRASOUND TO MONITOR PRENATAL GROWTH AND DEVELOPMENT IN THE COMMON MARMOSET (CALLITHRIX-JACCHUS)
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DOI：
10.1002/ajp.1350360402
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发表时间：
1995-01-01
影响因子：
2.4
通讯作者：
CARSON, RL
中科院分区：
文献类型：
--
作者：
JAQUISH, CE;TOAL, RL;CARSON, RL
越来越多地使用非人类灵长类动物来研究胎儿发育和新生儿管理，这就需要有已知妊娠史的胎儿。本研究利用超声技术对普通绒猴（Callithrix: jacchus）的产前发育和生长进行了研究。本研究的目的是：(1)确定超声监测普通狨猴产前生长发育的准确性；(2)确定产仔数是否影响产前生长轨迹；(3)评估产仔配偶之间的生长不一致性。采用实时腹部超声对50例妊娠进行纵向监测。每次检查时记录胎儿数量，测量冠臀长（CRL）和双顶径（BPD）。结果表明，超声是一种可靠的方法来观察大体形态变化在该物种的产前发育。妊娠早期超声测量的CRL和BPD与肉眼标本的测量结果一致。三胞胎的BPD和CRL均显著小于双胞胎（P < 0.05）。在CRL和BPD中，凋落物数与凋落物内变异无显著相关。本研究首次对紫锥菊的产前生长发育进行了纵向研究。本研究的观察结果将用于确定胎儿的大致胎龄，并为该物种的妊娠常规监测提供指导。(C) 1995 Wiley-Liss, Inc。
The increasing use of non-human primates to study fetal development and neonatal management has necessitated the availability of fetuses of known gestational history. In this study, prenatal development and growth were investigated in the common marmoset (Callithrix: jacchus) using ultrasound. The objectives of this study were: (1) to determine the accuracy of ultrasound for monitoring prenatal growth and development in common marmosets, (2) to determine if litter size influences prenatal growth trajectories, and (3) to assess growth discordancy among litter mates. Fifty pregnancies were monitored longitudinally using real-time abdominal sonography. During each examination the number of fetuses was recorded, and crown-rump length (CRL) and biparietal diameter (BPD) were measured. The results indicate that ultrasound is a reliable method for observation of gross morphological changes during prenatal development in this species. Measures of CRL and BPD taken early in gestation using ultrasound were in agreement with those from gross specimens. Triplets were significantly (P < 0.05) smaller than twins for both BPD and CRL. No significant relationship was found between litter size and within litter variation in CRL or BPD. This study is the first longitudinal investigation of prenatal growth and development in C. jacchus. The observations from this study will be of use for determining approximate gestational age of fetuses, as well as providing guidelines for routine monitoring of pregnancy in this species. (C) 1995 Wiley-Liss, Inc.