TRP Channels
TRP Channels
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DOI:
10.1002/cphy.c110026
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发表时间:
2012-01-01
影响因子:
5.8
通讯作者:
Voets, Thomas
中科院分区:
文献类型:
--
作者:
Gees, Maarten;Owsianik, Grzegorz;Voets, Thomas
TRP channels constitute a large superfamily of cation channel forming proteins, all related to the gene product of the transient receptor potential (trp) locus in Drosophila. In mammals, 28 different TRP channel genes have been identified, which exhibit a large variety of functional properties and play diverse cellular and physiological roles. In this article, we provide a brief and systematic summary of expression, function, and (patho)physiological role of the mammalian TRP channels. (C) 2012 American Physiological Society. Compr Physiol 2: 563-608, 2012.