A Comprehensive Review of Topical Odor-Controlling Treatment Options for Chronic Wounds.
A Comprehensive Review of Topical Odor-Controlling Treatment Options for Chronic Wounds.
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DOI：
10.1097/won.0000000000000273
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发表时间：
2016
期刊：
影响因子：
--
通讯作者：
Mikhalovsky S
中科院分区：
文献类型：
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作者：
Akhmetova A;Saliev T;Allan IU;Illsley MJ;Nurgozhin T;Mikhalovsky S
创面愈合过程中常伴有细菌感染或严重定植，导致长期炎症、延迟再上皮化和产生刺激性气味。这些伤口产生的恶臭可能会降低与健康相关的生活质量，并产生心理不适和社会孤立。目前的管理重点是减少伤口部位的细菌活动和吸收恶臭气体。例如，在敷料中加入了以木炭为基础的材料，以直接吸附负责的气体。此外，建议在敷料中加入多种外用制剂，包括银、碘、蜂蜜、糖和精油，以试图控制潜在的细菌感染。这篇综述描述了控制慢性创面恶臭的选择，每种外用药物的优点和缺点，以及它们的作用模式。我们还讨论了使用主观气味评估技术来评估气味控制治疗的有效性。展望了新型生物材料和技术在创面气味处理中的应用前景。
The process of wound healing is often accompanied by bacterial infection or critical colonization, resulting in protracted inflammation, delayed reepithelization, and production of pungent odors. The malodor produced by these wounds may lower health-related quality of life and produce psychological discomfort and social isolation. Current management focuses on reducing bacterial activity within the wound site and absorbing malodorous gases. For example, charcoal-based materials have been incorporated into dressing for direct adsorption of the responsible gases. In addition, multiple topical agents, including silver, iodine, honey, sugar, and essential oils, have been suggested for incorporation into dressings in an attempt to control the underlying bacterial infection. This review describes options for controlling malodor in chronic wounds, the benefits and drawbacks of each topical agent, and their mode of action. We also discuss the use of subjective odor evaluation techniques to assess the efficacy of odor-controlling therapies. The perspectives of employing novel biomaterials and technologies for wound odor management are also presented.