The rat MIS1/Pvt-1 locus is syntenic with MYC on chromosome 7.
The rat MIS1/Pvt-1 locus is syntenic with MYC on chromosome 7.
复制标题
大鼠 MIS1/Pvt-1 基因座与 7 号染色体上的 MYC 同线。
DOI:
10.1159/000132450
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发表时间:
1987
期刊:
影响因子:
--
通讯作者:
Sümegi,J
中科院分区:
文献类型:
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作者:
Ingvarsson,S;Wirschubsky,Z;Szpirer,J;Levan,G;Klein,G;Sümegi,J
MousePvt-1and rat MISl are frequent proviral integration sites in retrovirally induced lymphomas. ThePvt-1locus is also involved in mouse plasmacytoma (6;15) and in the variant Burkitt lymphoma (2;8) translocations. We show that the Pvt-1/MISl locus is syntenic with MYC on rat chromosome 7. This is consistent with a postulate of close linkage and, possibly, a functional relationship between the MYC protoon-cogene and the MIS1/Pvt-1 locus.