Worthing physiological scoring system: derivation and validation of a physiological early-warning system for medical admissions. An observational, population-based single-centre study

Worthing physiological scoring system: derivation and validation of a physiological early-warning system for medical admissions. An observational, population-based single-centre study
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DOI:
10.1093/bja/aem097
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发表时间:
2007-06-01
影响因子:
9.8
通讯作者:
Forni, L. G.
Forni, L. G.
中科院分区:
医学1区
文献类型:
--
作者:
Duckitt, R. W.;Buxton-Thomas, R.;Forni, L. G.

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背景。几种生理评分系统(PSS)已被提出用于识别那些有恶化风险的人。然而,所选择的特定生理值和分配的分数尚未得到前瞻性验证。在这项研究中,我们研究了通气频率、心率、动脉压、温度、氧饱和度和意识水平对死亡率的相对贡献,以便设计一个强大的评分系统。所有数据都是在急诊室入院时收集的。然后可以推导出精确的“干预召唤分数”来触发干预。我们的观察性、基于人群的单中心研究在一家拥有602个床位的地区综合医院进行。在2003年7月至11月的初步研究期间(n=3184)和2005年10月至11月的进一步验证期间(n=1102),纳入了Worthing综合医院急诊病房收治的患者。多因素logistic回归分析表明:通气频率>= 20 min(-1),心率>= 102 min(-1),收缩压= 35.3℃,血氧饱和度
Background. Several physiological scoring systems (PSS) have been proposed for identifying those at risk of deterioration. However, the chosen specific physiological values chosen and the scores allocated have not been prospectively validated. In this study, we investigate the relative contributions of the ventilatory frequency, heart rate, arterial pressure, temperature, oxygen saturation, and conscious level to mortality in order to devise a robust scoring system. All data were collected on admission to the emergency unit. Precise 'intervention-calling scores' could then be derived to trigger interventions.Methods. Our observational, population-based single-centred study took place in a 602-bedded district general hospital. Patients admitted to the emergency care unit at Worthing general hospital during an initial study period between July and November 2003 (n=3184) and a further validation period between October and November 2005 (n=1102) were included.Results. Multivariate logistic regression analysis demonstrated that a ventilatory frequency > 20 min(-1), heart rate >= 102 min(-1), systolic blood pressure = 35.3 degrees C, oxygen saturation