High-speed spectral-domain optical coherence tomography at 1.3 μm wavelength
High-speed spectral-domain optical coherence tomography at 1.3 μm wavelength
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DOI：
10.1364/oe.11.003598
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发表时间：
2003-12-29
期刊：
影响因子：
3.8
通讯作者：
de Boer, JF
中科院分区：
文献类型：
--
作者：
Yun, SH;Tearney, GJ;de Boer, JF
我们展示了一个高速谱域光学相干断层扫描（SD-OCT）系统能够获得个人的轴向扫描在24.4 μ s的速度为每秒19,000轴向扫描，使用InGaAs线扫描相机和宽带光源中心在1.31妈妈。超过2毫米的深度范围内的灵敏度>105分贝，获得了自由空间轴向分辨率为12-14妈妈，与我们的信噪比预测一致。使用SD-OCT在体内获得的人体组织图像显示出与使用最先进的时域OCT获得的穿透深度相似的穿透深度，尽管图像采集速度高出十倍。这些结果表明，1.3妈妈SD-OCT的高速和高灵敏度成像的患者的潜力。(C)2003年美国光学学会。
We demonstrate a high-speed spectral domain optical coherence tomography (SD-OCT) system capable of acquiring individual axial scans in 24.4 mus at a rate of 19,000 axial scans per second, using an InGaAs line scan camera and broadband light source centered at 1.31 mum. Sensitivity of >105 dB over a 2-mm depth range was obtained with a free-space axial resolution of 12-14 mum, in agreement with our signal-to-noise ratio predictions. Images of human tissue obtained in vivo with SD-OCT show similar penetration depths to those obtained with state-of-the-art time domain OCT despite the ten-fold higher image acquisition speed. These results demonstrate the potential of 1.3 mum SD-OCT for high-speed and high-sensitivity imaging in patients. (C) 2003 Optical Society of America.