Cell adhesion and chondrogenesis in brachypod mouse limb mesenchyme: fragment fusion studies.
Cell adhesion and chondrogenesis in brachypod mouse limb mesenchyme: fragment fusion studies.
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短足小鼠肢体间充质的细胞粘附和软骨形成：片段融合研究。
DOI：
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发表时间：
1978
期刊：
影响因子：
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通讯作者：
W. A. Elmer
中科院分区：
文献类型：
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作者：
J. Duke;W. A. Elmer
这项研究是对短足小鼠突变对早期肢体发育过程中细胞相互作用和软骨形成的影响的持续研究。在本报告中，评估了短足动物和正常肢芽间充质融合片段的细胞粘附性。对融合的远端后轴肢体碎片界面的检查显示短足肢体间质比正常肢体间质更具粘附性。短足动物碎片内的软骨形成比正常碎片延迟且范围较小。此外，正常片段内的软骨形成不受短足动物片段并置的影响，反之亦然。
This study is a continuing investigation of the effect of the brachypod mouse mutation on cell interactions and chondrogenesis during early limb development. In this report, cell adhesiveness was assessed in fused fragments of brachypod and normal limb-bud mesenchyme. Examination of the interface of fused distal postaxial limb fragments show brachypod limb mesenchyme to be more adhesive than normal limb mesenchyme. Chondrogenesis within brachypod fragments is delayed and less extensive than in normal fragments. In addition, chondrogenesis within normal fragments is not affected by the juxtaposition of the brachypod fragment, and vice versa.