Widespread Occurrence and Lateral Transfer of the Cyanobactin Biosynthesis Gene Cluster in Cyanobacteria
Widespread Occurrence and Lateral Transfer of the Cyanobactin Biosynthesis Gene Cluster in Cyanobacteria
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DOI：
10.1128/aem.02134-08
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发表时间：
2009-02-01
影响因子：
4.4
通讯作者：
Sivonen, Kaarina
中科院分区：
文献类型：
--
作者：
Leikoski, Niina;Fewer, David P.;Sivonen, Kaarina
蓝细菌素是由蓝细菌产生的小分子环状肽。在这里，我们证明了广泛的，但零星发生的氰基菌素生物合成途径。我们在本研究中包括的132株菌株中的48株中检测到氰基菌素生物合成基因。我们的研究结果表明，蓝藻菌素生物合成基因在蓝藻中有一个复杂的进化历史，由一系列古老的水平基因转移事件打断。
Cyanobactins are small cyclic peptides produced by cyanobacteria. Here we demonstrate the widespread but sporadic occurrence of the cyanobactin biosynthetic pathway. We detected a cyanobactin biosynthetic gene in 48 of the 132 strains included in this study. Our results suggest that cyanobactin biosynthetic genes have a complex evolutionary history in cyanobacteria punctuated by a series of ancient horizontal gene transfer events.