Evaluation and comparison of coagulation factor activity in fresh‐frozen plasma and 24‐hour plasma at thaw and after 120 hours of 1 to 6°C storage

Evaluation and comparison of coagulation factor activity in fresh‐frozen plasma and 24‐hour plasma at thaw and after 120 hours of 1 to 6°C storage
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DOI:
10.1111/j.1537-2995.2009.02198.x
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发表时间:
2009-08
期刊:
影响因子:
2.9
通讯作者:
Erik A. Scott;K. Puca;Jennifer Heraly;J. Gottschall;K. Friedman
Erik A. Scott;K. Puca;Jennifer Heraly;J. Gottschall;K. Friedman
中科院分区:
医学3区
文献类型:
--
作者:
Erik A. Scott;K. Puca;Jennifer Heraly;J. Gottschall;K. Friedman

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BACKGROUND: Current transfusion‐related acute lung injury reduction strategies include avoiding transfusion of plasma products collected from female donors or female donors that have been pregnant to reduce transfusion of plasma‐containing HLA antibodies. Such a policy considerably decreases the number of donors available for generation of fresh‐frozen plasma (FFP). To increase the supply of FFP, substitution of 24‐hour plasma (FP24) and thawed plasma (TP) derived from either FFP or FP24 may be viable substitutes. To justify such a policy the coagulation factor content of FFP, FP24, and TP derived from both product types was assessed.