Personality profile and neuropsychological test performance in chronic cocaine-abusers

Personality profile and neuropsychological test performance in chronic cocaine-abusers
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DOI:
10.3109/00207450108994221
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发表时间:
2001-01-01
影响因子:
2.2
通讯作者:
King, K
King, K
中科院分区:
医学4区
文献类型:
--
作者:
Rosselli, M;Ardila, A;King, K

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关于慢性可卡因使用者的人格障碍和神经心理学测试表现之间的关联知之甚少。本研究的目的是(1)确定慢性可卡因滥用者的特定神经心理学特征,(2)分析他们的人格特征,(3)探讨人格特征与神经心理测试成绩之间的关系。从国家康复机构中选择了42名药物滥用者(平均年龄= 34.15; SD = 6.73;平均教育水平= 11.44; SD = 2.01),并与对照组(平均年龄= 34.53; SD = 9.01;平均教育水平= 12.29; SD = 1.31)进行了比较。收集每例受试者的以下信息:(1)改编自Horton(1996)的临床病史。(2)人格评估量表(派)(Morey,1991)。(3)神经心理学成套测试包括:WAIS-R的算术和数字子测试、加州言语学习测试、试做测试、言语流畅性测试、Rey-Osterrieth复杂图形、威斯康星州卡片分类测试、本顿视觉保持测试、Stroop神经筛选测试和胡珀视觉组织。37名药物依赖受试者在至少一个派量表中获得异常评分。通过派发现的药物依赖受试者的人格特征指向边缘/反社会人格,通常与躁狂症特征相关。在6名药物滥用者中,观察到了正常的人格特征。神经心理学测试表现得分在低平均值或边界范围内。在注意力、记忆力和执行功能测试中观察到最异常的分数。结果并没有显示出人格特征和神经心理学测试表现之间有任何强有力的联系。
Little is known about the association between personality disorders and neuropsychological test performance in chronic cocaine users. The aims of the present study were to (1) pinpoint the specific neuropsychological characteristics of chronic cocaine abusers, (2) analyze their personality profile, and (3) explore the association between personality traits and neuropsychological test performance. A sample of 42 drug-abusers (mean age = 34.15; SD = 6.73; mean educational level = 11.44; SD = 2.01) was selected from a state rehabilitation facility and was compared to a control group (mean age = 34.53; SD = 9.01; mean educational level = 12.29; SD = 1.31). The following information was collected for each subject: (1) A clinical history adapted from Horton (1996). (2) The Personality Assessment Inventory (PAI) (Morey, 1991). (3) A neuropsychological test battery including: Arithmetic and Digits subtests from the WAIS-R, California Verbal Learning Test, Trial Making Test, Verbal Fluency tests, Rey-Osterrieth Complex Figure, Wisconsin Card Sorting Test, Benton Visual Retention Test, Stroop Neurological Screening Test and Hooper Visual Organization. Thirty-seven of the drug-dependent subjects obtained an abnormal score in at least one PAI scale. The personality profile of the drug-dependent subjects found via the PAI pointed to a Borderline/Antisocial personality, frequently associated with mania features. In six of the drug-abusers, a normal personality profile was observed. Neuropsychological test performance scores were within the low average or borderline range. The most abnormal scores were observed in attention, memory, and executive functioning tests. The results did not show any robust association between personality profile and neuropsychological test performance.