SUBCELLULAR LOCALIZATION OF N‐ACETYL‐ASPARTYL‐GLUTAMATE, N‐ACETYL‐GLUTAMATE AND GLUTATHIONE IN BRAIN

SUBCELLULAR LOCALIZATION OF N‐ACETYL‐ASPARTYL‐GLUTAMATE, N‐ACETYL‐GLUTAMATE AND GLUTATHIONE IN BRAIN
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N-乙酰-天冬氨酰-谷氨酸、N-乙酰-谷氨酸和谷胱甘肽在脑中的亚细胞定位

DOI:
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发表时间:
1969
影响因子:
4.7
通讯作者:
F. Fonnum
F. Fonnum
中科院分区:
医学2区
文献类型:
--
作者:
K. L. Reichelt;F. Fonnum

文献摘要

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摘要研究了N-乙酰天冬氨酸、N-乙酰天冬氨酸、N-乙酰谷氨酸和还原型谷胱甘肽的亚细胞分布。用乳酸脱氢酶、钾、谷氨酸和天冬氨酸作为细胞质的标志。富马酸水合酶和胆碱乙酰转移酶分别作为线粒体和突触体标记物。
Abstract— The subcellular distribution of N‐acetyl‐aspartate, N‐acetyl‐aspartyl‐glutamate, N‐acetyl‐glutamate and glutathione (reduced) was investigated. Lactate dehydrogenase, potassium, glutamate and aspartate were employed as markers of the cytoplasmatic compartments. Fumarate hydratase and choline acetyltransferase were used as mitochondrial and synaptosomal markers respectively.