Impact of postnatal depression on infants' growth in Nigeria

Impact of postnatal depression on infants' growth in Nigeria
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DOI:
10.1016/j.jad.2007.09.013
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发表时间:
2008-05-01
影响因子:
6.6
通讯作者:
Okeniyi, John A. O.
Okeniyi, John A. O.
中科院分区:
医学2区
文献类型:
--
作者:
Adewuya, Abiodun O.;Ola, Bola O.;Okeniyi, John A. O.

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背景:非洲产妇产后抑郁症对婴儿生长和营养不良的影响尚未得到很好的研究。本研究旨在探讨产后抑郁症(PND)对婴儿在出生后前9个月的身体发育的影响,在尼日利亚.方法:纵向病例对照研究中,242名妇女(包括120名抑郁症和122名匹配的非抑郁症产后妇女)在分娩后6周,3个月,6个月和9个月测量婴儿的体重和身长。结果:抑郁症母亲的婴儿在3个月时的生长发育明显低于非抑郁症母亲的婴儿(体重OR 3.41,95%CI 1.30-8.52;身长OR 3.28,95%CI 1.03-10.47)和产后6个月(体重OR 4.21,95%CI 1.36-13.20;身长OR 3.34,95%CI 1.18-9.52)。抑郁的母亲更有可能提前停止母乳喂养,她们的婴儿更有可能出现腹泻和其他传染病。(在产后6周),我们的样本量是中等的,我们没有考虑到母亲谁曾在怀孕期间抑郁。预防产后抑郁症和密切监测抑郁症母亲的婴儿的成长应纳入该区域的妇幼保健政策。(C)2007 Elsevier B. V.保留所有权利。
Background: The contribution of maternal postnatal depression to infant growth and under-nutrition in Africa has not been well studied. This study aims to examine the impact of postnatal depression (PND) on infants' physical growth in the first 9 months of life in Nigeria.Methods: A longitudinal case controlled study in which 242 women (consisting of 120 depressed and 122 matched non-depressed postpartum women) bad their infants' weight and length measured at the 6th week, 3rd month, 6th month and 9th month after delivery. Discontinuation with breastfeeding and illnesses like diarrhoea, persistent vomiting, fever and cough were also recorded at these periods.Results: Infants of depressed mothers had statistically significant poorer growth than infants of non-depressed mothers at the 3rd month (weight OR 3.41, 95% CI 1.30-8.52; length OR 3.28, 95% CI 1.03-10.47) and the 6th month postpartum (weight OR 4.21, 95% CI 1.36-13.20; length OR 3.34, 95% CI 1.18-9.52). Depressed mothers were more likely to stop breastfeeding earlier and their infants more likely to have episodes of diarrhoea and other infectious illnesses.Limitations: Psychiatric interview was conducted only once (at 6 weeks postpartum), our sample size was moderate and we did not account for mothers who had been depressed in pregnancy.Conclusion: Prevention of postnatal depression and close monitoring of the growth of infants of depressed mothers should be integrated into maternal and child health policies in this region. (C) 2007 Elsevier B.V. All rights reserved.