Correlation between parathyroid hormone, bone alkaline phosphatase and N-telopeptide of type 1 collagen in diabetic and non-diabetic haemodialysis patients
Correlation between parathyroid hormone, bone alkaline phosphatase and N-telopeptide of type 1 collagen in diabetic and non-diabetic haemodialysis patients
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DOI：
10.1111/j.1440-1797.2007.00829.x
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发表时间：
2007-12-01
期刊：
影响因子：
2.5
通讯作者：
Ishiguro, Naoki
中科院分区：
文献类型：
--
作者：
Takahashi, Nobunori;Kojima, Toshihisa;Ishiguro, Naoki
背景资料：糖尿病血液透析（HD）患者常伴有以骨转换减少为特征的肾性骨营养不良（ROD），但对这一人群中骨形成和骨吸收之间的相关性知之甚少。作者测定了血清甲状旁腺激素（PTH）、骨碱性磷酸酶（BAP）、对48例糖尿病肾病（DN）和80例肾小球肾炎（非DN）患者进行了1型胶原N端肽（NTx）和空腹血糖的检测，
Background: Haemodialysis(HD) patients with diabetes mellitus often have renal osteodystrophy (ROD) characterized by reduced bone turnover, but little is known about the correlation between bone formation and bone resorption in this population.Methods: The authors measured serum parathyroid hormone (PTH), bone alkaline phosphatase (BAP), N-telopeptides of type 1 collagen (NTx) and fasting glucose in 48 patients with diabetic nephropathy (DN) and 80 patients with glomerulonephritis (non-DN) who had received