Hypopnea, a floating metric: Implications for prevalence, morbidity estimates, and case finding
Hypopnea, a floating metric: Implications for prevalence, morbidity estimates, and case finding
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DOI：
10.1093/sleep/20.12.1209
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发表时间：
1997-01-01
期刊：
影响因子：
5.6
通讯作者：
Sanders, M
中科院分区：
文献类型：
--
作者：
Redline, S;Sanders, M
呼吸障碍指数（RDI）是表征睡眠呼吸障碍最常用的指标。在临床上，RDI用于疾病状态分类和指导治疗决策。出于研究目的，RDI被用来描述睡眠呼吸障碍的人口分布。然而，它作为一种主要疾病定义措施的流行可能并不合理，因为定义低通气的标准化标准不存在，而低通气是RDI的一个关键组成部分。本文回顾了识别低呼吸的可变性来源，包括：描述呼吸“减少”所需的呼吸幅度变化幅度（从“可识别”到50%），不同灵敏度传感器检测气流/通风（即热电偶，热敏电阻和压力传感器）的使用变化，以及区分正常呼吸和低呼吸的氧饱和度和唤醒数据的不同使用。不同的方法对总体RDI和疾病人口估计的影响程度也进行了讨论。
The respiratory disturbance index (RDI) is the most frequently used metric to characterize sleep-disordered breathing. Clinically, the RDI is used to classify disease status and guide treatment decisions. For research purposes, the RDI is used to describe population distributions of sleep-disordered breathing. Its popularity as a cardinal disease-defining measure, however, may not be justified given that standardized criteria do not exist for defining hypopnea, a key component of the RDI. This paper reviews sources of variability in identifying hypopneas, including: the magnitude of changes in breathing amplitude necessary to describe breathing as "reduced" (from "discernible" to >50%), variations in the utilization of sensors with different sensitivities to detect airflow/ventilation (i.e. thermocouples, thermistors, and pressure transducers), and differential use of data on oxygen saturation and arousals to discriminate normal breathing from hypopneas. The extent to which disparate approaches influence the overall RDI and population estimates of disease also is discussed.