Highly cross-linked polyethylene - The debate is over - In the affirmative
Highly cross-linked polyethylene - The debate is over - In the affirmative
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DOI：
10.1016/j.arth.2005.03.015
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发表时间：
2005-06-01
影响因子：
3.5
通讯作者：
Muratoglu, O
中科院分区：
文献类型：
--
作者：
Jasty, M;Rubash, HE;Muratoglu, O
高度辐射交联、随后熔融的超高分子量聚乙烯（XLP）在全关节置换术中作为显著减少磨损和相关假体周围骨质溶解的一种手段，已迅速获得广泛认可。几项实验室研究表明，在模拟20年体内使用的持续时间内，XLP在髋关节和膝关节中的磨损可忽略不计。涉及3个不同人口统计学组和2种不同测量技术的3项临床研究发现，植入后股骨头穿透率小于10 mm/y。插入后3年的髋臼和胫骨样本回收证实没有磨损和氧化。根据5年的体内经验，XLP似乎是全关节置换术的首选材料。(c)2005年爱思唯尔公司All rights reserved.
Highly radiation-cross-linked, subsequently melted ultralligh molecular weight polyethylene (XLP) has rapidly gained wide acceptance in total joint arthroplasty as a means to markedly reduce wear and the associated periprosthetic osteolysis. Several laboratory studies have shown negligible wear of XLP in both hip and knee for durations simulating 20 years of in vivo service. Three clinical studies involving 3 different demographic groups and 2 different measurement techniques have found that the femoral head penetration after bedding-in is less than 10 mm/y. Retrieval acetabular and tibial specimens up to 3 years after insertion have confirmed the absence of wear and oxidation. With in vivo experience now over 5 years, it appears that XLP is the material of choice in total joint arthroplasty. (c) 2005 Elsevier Inc. All rights reserved.