Validity of sleep nasendoscopy in the investigation of sleep related breathing disorders
Validity of sleep nasendoscopy in the investigation of sleep related breathing disorders
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DOI：
10.1097/01.mlg.0000157849.16649.6e
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发表时间：
2005-03-01
期刊：
影响因子：
2.6
通讯作者：
Whittet, HB
中科院分区：
文献类型：
--
作者：
Berry, S;Roblin, G;Whittet, HB
目标。目的：验证睡眠鼻内镜在有症状患者和无症状对照组中应用靶标控制输注的技术。设计：前瞻性队列研究。设置。某教学医院耳鼻咽喉头颈外科及麻醉科。参与者。对两组患者的身体质量指数进行比较和匹配。第一组包括53名有阻塞性睡眠呼吸暂停病史的患者。第二组由54名伴侣证实无打鼾史的患者组成。这些病人因其他原因接受麻醉。两组患者均无相关耳鼻喉科症状。主要结果测量。丙泊酚靶控输注镇静作为全身麻醉的一部分对无打鼾史患者打鼾或梗阻的评估结果与结论：与有症状组比较，无症状组在任何剂量的异丙酚下均无打鼾或梗阻，差异有统计学意义（P < 0.001）。所有有症状的患者均被诱导出现症状（打鼾/梗阻）。
Objective. To validate the technique of sleep nasendoscopy using target controlled infusion in symptomatic patients and a control group of asymptomatic individuals. Design: Prospective cohort study. Setting. Department of otolaryngology-head and neck surgery and anesthesia in a teaching hospital. Participants. Two groups of patients were compared and matched for their body mass index. The first group consisted of 53 patients with a history suggestive of obstructive sleep apnea. The second group consisted of 54 patients with partner-confirmed history of no snoring. These patients were undergoing anesthesia for other reasons. Both groups of patients were free of associated otorhinolaryngologic symptoms. Main Outcome Measure. Assessment of production of snoring or obstruction in patients with no documented history of snoring when sedation was administered as part of general anesthesia using target controlled infusion with propofol. Results and Conclusions: None of the patients in the asymptomatic group snored or obstructed at any level of propofol, and this was clearly significant on comparison with the symptomatic group (P < .001). All of the symptomatic patients were induced to become symptomatic (snoring/obstruction).