Tetrahymena Gene Expression Database (TGED): A resource of microarray data and co-expression analyses for Tetrahymena
Tetrahymena Gene Expression Database (TGED): A resource of microarray data and co-expression analyses for Tetrahymena
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四膜虫基因表达数据库 (TGED)：四膜虫微阵列数据和共表达分析的资源
DOI：
10.1007/s11427-010-4114-1
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发表时间：
2011-01-01
影响因子：
9.1
通讯作者：
Miao Wei
中科院分区：
文献类型：
--
作者：
Xiong Jie;Lu XingYi;Miao Wei
嗜热四膜虫是一种模式真核生物。四膜虫的功能基因组分析为解决细胞和分子生物学的基本问题提供了丰富的机会。四膜虫基因表达数据库（TGED;可在http://tged.ihb.ac.cn获得）是纤毛原生动物的第一个表达数据库。它涵盖了三个主要的生理和发育状态：生长，饥饿和接合，并可以通过用户友好的Web界面访问。每个基因的基因表达谱和候选共表达基因可以使用基因ID或基因描述搜索来检索。标准化的样品制备方法的描述和添加新的四膜虫微阵列数据的机会将是四膜虫研究界的极大兴趣。TGED旨在成为对四膜虫和其他纤毛虫感兴趣的科学研究社区的所有成员的资源。
Tetrahymena thermophila is a model eukaryotic organism. Functional genomic analyses in Tetrahymena present rich opportunities to address fundamental questions of cell and molecular biology. The Tetrahymena Gene Expression Database (TGED; available at http://tged.ihb.ac.cn) is the first expression database of a ciliated protozoan. It covers three major physiological and developmental states: growth, starvation, and conjugation, and can be accessed through a user-friendly web interface. The gene expression profiles and candidate co-expressed genes for each gene can be retrieved using Gene ID or Gene description searches. Descriptions of standardized methods of sample preparation and the opportunity to add new Tetrahymena microarray data will be of great interest to the Tetrahymena research community. TGED is intended to be a resource for all members of the scientific research community who are interested in Tetrahymena and other ciliates.