Prospective association of occupational and leisure-time physical activity with orthostatic blood pressure changes in older adults.
Prospective association of occupational and leisure-time physical activity with orthostatic blood pressure changes in older adults.
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DOI：
10.1038/s41598-023-46947-7
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发表时间：
2023-11-24
影响因子：
4.6
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中科院分区：
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直立性低血压（OH）在老年人中很常见。我们研究了老年人样本在两年内自我报告的职业相关体力活动 (PA) 和休闲体育锻炼 (PE) 对直立反应的影响。在基线和 2 年随访中，对 205 名老年受试者（> 60 岁）的仰卧位和直立位收缩压 (sBP)、舒张压 (dBP) 和平均血压 (mBP) 进行了评估，以响应 Active Stand (AS) 测试。基线时有 24 名受试者 (11.71%) 发现 OH，2 年后有 20 名受试者 (9.76%) 发现 OH，2 年后 OH 的发生率存在显着差异。 22 名在基线时患有 OH 的受试者在 2 年后痊愈，两名受试者在基线时和 2 年后患有持续性 OH。 2 年后，患有职业性 PA 的成年人对 AS 测试的反应没有表现出血压显着下降，而缺乏进行职业相关的 PA 与 AS 测试后第 1 分钟的 sBP 和 mBP 大幅下降显着相关。职业相关的 PA 和休闲时间相关的 PE 与基线和 2 年后血压对 AS 的反应增加有关。注意到 2 年来受试者之间的 OH 差异很大。中年时期从事持续体育活动和休闲体育锻炼的职业对于 2 年内直立性压力测试中的血压下降都有保护作用。
Orthostatic hypotension (OH) is common in older people. We examined the influence of self-reported occupational-related physical activity (PA) and leisure-time physical exercise (PE) on orthostatic response in a sample of older people over a 2 year period. Supine and orthostatic systolic blood pressure (sBP), diastolic blood pressure (dBP), and mean blood pressure (mBP) were assessed in response to Active Stand (AS) test in 205 older subjects (> 60 years old) at baseline and 2-year follow-up. OH was found in 24 subjects (11.71%) at baseline and 20 subjects (9.76%) after 2 years, with a significant degree of variability in the occurrence of OH after 2 years. Twenty-two subjects who had OH at baseline were free of it after 2 years, two subjects had persistent OH at baseline and after 2 years. After 2 years, adults with occupational PA showed no significant decrease of blood pressure in response to AS test, while lack of undertaking an occupation-related PA was significantly related with a greater decrease in sBP and mBP in response to AS testing in the 1st min. Occupation-related PA and leisure-time-related PE were related to an increase in the response of BP on AS in change between baseline and after 2 years. High between-subjects variance in OH over 2 years was noted. Occupations that involved continuous physical activity and leisure-time physical exercise in middle age were both protective for BP decline on orthostatic stress test within 2 years.