The Susceptibility to Other Infectious Diseases Following Measles During a Three Year Observation Period in Switzerland
The Susceptibility to Other Infectious Diseases Following Measles During a Three Year Observation Period in Switzerland
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DOI：
10.1097/inf.0000000000002599
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发表时间：
2020-06-01
影响因子：
3.6
通讯作者：
Heininger, Ulrich
中科院分区：
文献类型：
--
作者：
Behrens, Lynn;Cherry, James D.;Heininger, Ulrich
背景：麻疹病毒感染导致显著的免疫抑制。在发展中国家，这转化为非特异性死亡率的增加，而其在发达国家的影响则不那么清楚。方法：我们进行了一项队列研究，以调查2000年至2015年期间在瑞士因麻疹住院的儿童（病例）是否会比未患麻疹的儿童（对照组）此后因其他传染病住院的频率更高。病例通过ICD-10麻疹出院诊断和/或关键词检索确定，并按住院时间、年龄和性别与2名对照组匹配。所有住院
Background:Measles virus infection leads to significant immunosuppression. In developing countries, this translates to an increased nonspecific mortality, whereas its effects in developed countries are less clear.Methods:We performed a cohort study to investigate whether children hospitalized with measles (cases) between 2000 and 2015 in Switzerland would have a higher frequency of hospital admissions due to other infectious diseases thereafter than children who did not have measles (controls). Cases were identified by ICD-10 discharge diagnoses for measles and/or keyword search and matched to 2 controls by time of hospitalization, age and sex. All hospitalizations