Diabetes and Cognitive Decline: Investigating the Potential Influence of Factors Related to Health Disparities

Diabetes and Cognitive Decline: Investigating the Potential Influence of Factors Related to Health Disparities
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DOI:
10.1177/0898264309357445
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发表时间:
2010-04-01
影响因子:
2.8
通讯作者:
Allman, Richard M.
Allman, Richard M.
中科院分区:
医学3区
文献类型:
--
作者:
Crowe, Michael;Sartori, Andrea;Allman, Richard M.

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目的:作者调查了与健康相关的因素种族、农村居住、教育、种族歧视、血管疾病、医疗保健的获得和利用是否可以缓和糖尿病和认知能力下降之间的关系。方法:参与者是624名社区居住的老年人(49%为非洲裔美国人,49%为农村人),他们在基线和4年随访时完成了家庭简易精神状态检查。结果:基线糖尿病预测四年认知能力下降的回归模型调整了一些可能的混淆。只有感知歧视和健康利用与糖尿病有显著的交互作用。在报告遭受种族歧视的非裔美国人中,糖尿病和认知能力下降之间的关系更密切。在过去6个月内没有去看医生的参与者中,糖尿病和认知能力下降之间的关联要大得多。讨论:研究结果表明,与健康差异相关的因素可能会影响老年糖尿病患者的认知结果。
Objectives: The authors investigated whether factors related to health disparities-race, rural residence, education, perceived racial discrimination, vascular disease, and health care access and utilization-may moderate the association between diabetes and cognitive decline. Method: Participants were 624 community-dwelling older adults (49% African American and 49% rural) who completed in-home mini-mental state examination at baseline and 4-year follow-up. Results: Diabetes at baseline predicted four-year cognitive decline in regression models adjusted for a number of possible confounds. Only perceived discrimination and health utilization showed significant interaction effects with diabetes. Among African Americans who reported experiencing racial discrimination, there was a stronger relationship between diabetes and cognitive decline. Among participants who reported absence of visiting a physician within the past 6 months, the association between diabetes and cognitive decline was substantially larger. Discussion: Findings suggest that factors related to health disparities may influence cognitive outcomes among older adults with diabetes.