Attenuated sensitivity to the emotions of others by insular lesion.
Attenuated sensitivity to the emotions of others by insular lesion.
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DOI：
10.3389/fpsyg.2015.01314
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发表时间：
2015
影响因子：
3.8
通讯作者：
Umeda S
中科院分区：
文献类型：
--
作者：
Terasawa Y;Kurosaki Y;Ibata Y;Moriguchi Y;Umeda S
多年来，岛叶皮质一直被认为是内脏感觉的神经基础。心理学和认知神经科学之前的研究已经积累了证据，表明内感是情绪主观感觉的一个重要因素。最近的神经成像研究表明，前岛叶皮质的激活与获取内感信息和支持情绪状态的主观体验有关。只有少数研究集中于岛叶损伤对情绪加工和内感意识的影响。此外，对于岛叶病变对情绪处理的改变，已经提出了不同的假说。一些研究表明，岛状病变导致无法理解和仅代表厌恶，但其他研究表明，这种病变调节了对积极和负面情绪的唤醒和价位判断。在这项研究中，我们考察了三例右侧岛状及其邻近区域受损的患者的情绪识别变化，这些患者的认知功能都保持得很好。参与者使用中性和情绪化的面部表情(即愤怒、悲伤、厌恶和快乐)来执行一项实验任务。计算特定情绪的识别率来测量情绪敏感度。此外，他们还进行了心跳感知任务，以测量内部感觉的准确性。这些案例将唤醒程度较高的情绪(例如，愤怒)识别为较少唤起的情绪(例如，悲伤)，并且一个案例显示出极低的内感准确率。目前的结果表明，岛状损害会导致情感上的情感敏感性减弱，而不是类别特定的损害，如厌恶。尽管案例数量很少，但我们的发现表明，岛叶皮质调节对情绪突显的识别，并调节感觉间和情绪意识。
The insular cortex has been considered to be the neural base of visceral sensation for many years. Previous studies in psychology and cognitive neuroscience have accumulated evidence indicating that interoception is an essential factor in the subjective feeling of emotion. Recent neuroimaging studies have demonstrated that anterior insular cortex activation is associated with accessing interoceptive information and underpinning the subjective experience of emotional state. Only a small number of studies have focused on the influence of insular damage on emotion processing and interoceptive awareness. Moreover, disparate hypotheses have been proposed for the alteration of emotion processing by insular lesions. Some studies show that insular lesions yield an inability for understanding and representing disgust exclusively, but other studies suggest that such lesions modulate arousal and valence judgments for both positive and negative emotions. In this study, we examined the alteration in emotion recognition in three right insular and adjacent area damaged cases with well-preserved higher cognitive function. Participants performed an experimental task using morphed photos that ranged between neutral and emotional facial expressions (i.e., anger, sadness, disgust, and happiness). Recognition rates of particular emotions were calculated to measure emotional sensitivity. In addition, they performed heartbeat perception task for measuring interoceptive accuracy. The cases identified emotions that have high arousal level (e.g., anger) as less aroused emotions (e.g., sadness) and a case showed remarkably low interoceptive accuracy. The current results show that insular lesions lead to attenuated emotional sensitivity across emotions, rather than category-specific impairments such as to disgust. Despite the small number of cases, our findings suggest that the insular cortex modulates recognition of emotional saliency and mediates interoceptive and emotional awareness.