Parathyroid carcinoma. A study of 70 cases

Parathyroid carcinoma. A study of 70 cases
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甲状旁腺癌。

DOI:
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发表时间:
1973
期刊:
影响因子:
6.2
通讯作者:
B. Castleman
B. Castleman
中科院分区:
医学1区
文献类型:
--
作者:
A. Schantz;B. Castleman

文献摘要

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本文对40年来收集的70例甲状旁腺癌进行了分析。患者平均年龄44.3岁,无性别优势。最常见的体征和症状是骨骼疾病、可触及的颈部肿块和肾结石。初始血钙值平均为15.2 mg/100 ml。最重要的组织学特征是有丝分裂和纤维带。30%的病例发生局部复发。转移性扩散发生在30%的病例中,通常发生在晚期,并转移到局部淋巴结、肺、肝和骨。不到一半的患者在5年内死于这种疾病。
Seventy cases of carcinoma of the parathyroid collected over a 40‐year period are analyzed. The average age of the patients was 44.3 years, and there was no sex predominance. The most common presenting signs and symptoms were bone disease, a palpable neck mass, and renal stones. The initial serum calcium value averaged 15.2 mg/100 ml. The most important histologic features were mitoses and fibrous bands. Local recurrence occurred in 30% of the cases. Metastatic spread, which occurred in 30% of the cases, was usually late and to regional lymph nodes, lungs, liver, and bone. Less than half the patients died of the disease within 5 years.