Genetic characterization of an avian H4N6 influenza virus isolated from the Izumi plain, Japan
Genetic characterization of an avian H4N6 influenza virus isolated from the Izumi plain, Japan
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DOI：
10.1111/1348-0421.12545
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发表时间：
2017-11-01
影响因子：
2.6
通讯作者：
Ozawa, Makoto
中科院分区：
文献类型：
--
作者：
Okuya, Kosuke;Kanazawa, Norihiro;Ozawa, Makoto
2013年从日本泉平原分离出H4N6亚型的甲型流感病毒。基因分析显示，该分离株的两个病毒基因（M和NS基因片段）与2012年从同一地点分离的H4N6病毒的基因不同。此外，该分离株的三个病毒基因（PB2、PB1和M基因片段）与2014年北美分离株的基因具有高度相似性。这些结果表明，高频率的基因重组的禽流感病毒在亚洲水禽和洲际运动的禽流感病毒通过迁徙水禽。
An influenza A virus of H4N6 subtype was isolated from the Izumi plain, Japan, in 2013. Genetic analyses revealed that two viral genes (M and NS gene segments) of this isolate were genetically distinct from those of the H4N6 virus isolated from the same place in 2012. Furthermore, three viral genes (PB2, PB1 and M gene segments) of this isolate share high similarity with those of the North American isolates of 2014. These results suggest a high frequency of genetic reassortment of avian influenza viruses in Asian waterfowl and intercontinental movements of avian influenza viruses via migratory waterfowl.