Smell your memories: Positive effect of odor exposure on recent and remote autobiographical memories in Alzheimer's disease
Smell your memories: Positive effect of odor exposure on recent and remote autobiographical memories in Alzheimer's disease
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DOI：
10.1080/13803395.2019.1586840
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发表时间：
2019-03-16
影响因子：
2.2
通讯作者：
El Haj, Mohamad
中科院分区：
文献类型：
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作者：
Glachet, Ophelie;Moustafa, Ahmed. A.;El Haj, Mohamad
在阿尔茨海默病（AD）中，气味暴露对自传式记忆的影响正在引起人们的兴趣。我们通过评估气味暴露对阿尔茨海默病患者近期和远程记忆检索的影响来进行这方面的研究。方法：对26例轻度AD患者和28例对照患者进行气味暴露和无气味暴露两种情况下的测试。在每种情况下，参与者都被要求找回两段童年记忆、两段成年记忆和两段近期记忆。结果：分析表明，气味暴露后，AD患者产生的童年记忆、成年记忆和近期记忆的数量和特异性高于无气味者。讨论：这些发现证明了气味暴露如何减轻顺行性和逆行性健忘症，至少当考虑到轻度阿尔茨海默氏症患者恢复少量近期或远程记忆的能力时。
Introduction: There is a burgeoning interest in the effects of odor exposure on autobiographical memory in Alzheimer's disease (AD). We pursued this line of research by assessing the effect of odor exposure on the retrieval of recent and remote memories in AD. Method: Twenty-six patients with mild AD and 28 controls were tested in two conditions: with and without odor exposure. In each condition, participants were invited to retrieve two childhood memories, two adulthood memories, and two recent memories. Results: Analysis showed that AD patients produced a higher number of and more specific childhood memories, adulthood memories, and recent memories after odor exposure than without odor. Discussion: These findings demonstrate how odor exposure may alleviate anterograde and retrograde amnesia, at least when considering the ability of patients with mild AD to retrieve few recent or remote memories.