Transporting epithelia as targets for kinin effects.

Transporting epithelia as targets for kinin effects.
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运输上皮细胞作为激肽效应的靶标。

DOI:
10.1007/978-1-4684-5143-6_28
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发表时间:
1986
影响因子:
--
通讯作者:
MacVinish,LJ
MacVinish,LJ
中科院分区:
医学4区
文献类型:
--
作者:
Cuthbert,AW;MacVinish,LJ

文献摘要

被引文献

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可用于发现激肽释放酶-激肽系统功能的一种方法是假设组织激肽释放酶可以在组织中产生赖氨酰缓激肽(LBK,激肽),然后在组织中充当局部激素。如果这是真的,那么激肽的新作用可能会在激肽释放酶特别集中的组织中被发现。对这些影响的考虑可以得出关于激肽释放酶-激肽系统在生理或病理状态下的作用的一些结论。
One approach which can be used to discover the function(s) of the kallikrein-kinin system is to make the assumption that tissue kallikrein can generate lysyl bradykinin (LBK, kallidin) in tissues, where it then acts as local hormone. If this be true then it follows that novel effects of kinin may be discovered in tissues where kallikrein is especially localized. Consideration of these effects may then allow some conclusions to be drawn about the roles of the kallikrein-kinin system in either physiological or pathological states.