Draft Whole-Genome Sequences of Periodontal Pathobionts Porphyromonas gingivalis, Prevotella intermedia, and Tannerella forsythia Contain Phase-Variable Restriction-Modification Systems.
Draft Whole-Genome Sequences of Periodontal Pathobionts Porphyromonas gingivalis, Prevotella intermedia, and Tannerella forsythia Contain Phase-Variable Restriction-Modification Systems.
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DOI：
10.1128/genomea.01229-17
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发表时间：
2017-11-16
期刊：
影响因子：
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通讯作者：
Oggioni MR
中科院分区：
文献类型：
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作者：
Haigh RD;Crawford LA;Ralph JD;Wanford JJ;Vartoukian SR;Hijazi K;Wade W;Oggioni MR
牙周病包括轻微到严重的炎症宿主对口腔细菌的反应，可导致牙齿支撑组织的破坏。我们报告了18个临床分离的牙龈卟啉单胞菌，中间普雷沃菌和连日坦纳菌的基因组序列，革兰氏阴性专性厌氧菌在牙周病过程中发挥作用。
Periodontal disease comprises mild to severe inflammatory host responses to oral bacteria that can cause destruction of the tooth-supporting tissue. We report genome sequences for 18 clinical isolates of Porphyromonas gingivalis, Prevotella intermedia, and Tannerella forsythia, Gram-negative obligate anaerobes that play a role in the periodontal disease process.