Meniscal subluxation: association with osteoarthritis and joint space narrowing

Meniscal subluxation: association with osteoarthritis and joint space narrowing
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DOI:
10.1053/joca.1999.0256
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发表时间:
1999-11-01
影响因子:
7
通讯作者:
Felson, D
Felson, D
中科院分区:
医学2区
文献类型:
--
作者:
Gale, DR;Chaisson, CE;Felson, D

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目的:由于完全切除半月板导致膝关节骨性关节炎,我们调查了半月板半脱位、关节间隙变窄和症状性骨性关节炎之间的潜在联系。材料和方法。对233例有症状的膝关节骨性关节炎患者和58例无症状对照的膝关节进行了X线平片和核磁共振成像。在负重PA透视定位的X线片上测量关节间隙狭窄。在冠状面MR图像上测量内侧或外侧半月板半脱位的数量。比较病例和对照组半月板半脱位的患病率和严重程度。我们评估了半月板半脱位程度与关节间隙狭窄、Kellgren和Lawrence分级以及年龄和体重两个主要危险因素之间的相关性。结果:患者的内侧和外侧半脱位多于对照组。病例组平均内侧半月板半脱位5.1 mm,对照组平均2.8 mm(P=0.001)。中度半月板半脱位在病例组和对照组中均较常见:81%的病例和组的半月板半脱位大于或等于3 mm;调整了年龄和性别(P=0.006)。严重程度的半脱位几乎是骨性关节炎患者所特有的(例如,大于或等于7 mm的患病率,35%的病例与7%的对照组,P
Objective: Since complete meniscectomy leads to knee OA, we investigated the potential links among meniscal subluxation, joint space narrowing and symptomatic OA.Materials and methods. 233 cases with symptomatic knee OA and 58 asymptomatic controls underwent radiography and MR imaging of the knee. Joint space narrowing was measured on weight-bearing PA fluoroscopy-positioned radiographs. The amount of medial or lateral meniscal subluxation was measured on coronal MR images. The prevalence and severity of meniscal subluxation was compared in cases and controls. We evaluated the correlation of the degree of meniscal subluxation with joint space narrowing, Kellgren and Lawrence grade, and two major risk factors for the development of OA, age and weight.Results: Cases had more medial and lateral subluxation than controls. Mean medial meniscal subluxation was 5.1 mm in cases and 2.8 mm in controls (P=0.001). Modest degrees of meniscal subluxation were common in both cases and controls: 81% of cases and 64% of controls had greater than or equal to 3 mm of subluxation; age and gender adjusted (P=0.006). Severe degrees of subluxation were almost unique to OA cases (e.g. prevalence of greater than or equal to 7 mm, 35% cases vs. 7% controls, P