Antimicrobial secretions and social immunity in larval burying beetles, Nicrophorus vespilloides
Antimicrobial secretions and social immunity in larval burying beetles, Nicrophorus vespilloides
复制标题
DOI：
10.1016/j.anbehav.2013.07.008
复制
发表时间：
2013-10-01
期刊：
影响因子：
2.5
通讯作者：
Rozen, Daniel E.
中科院分区：
文献类型：
--
作者：
Arce, Andres N.;Smiseth, Per T.;Rozen, Daniel E.
许多动物的后代在暴露于高密度潜在有害细菌的环境中发育。例如，腐肉甲虫Nicrophorus vespilloides的幼虫在分解脊椎动物尸体的过程中遇到了细菌的严重挑战。我们测试了幼虫在发育过程中分泌抗菌化合物以保护自己免受微生物暴露的想法。我们首先发现，幼虫分泌的活性抗菌剂在发育的早期达到高峰。正如先前已经发现的亲本分泌物，幼虫分泌物对革兰氏阳性但不是革兰氏阴性细菌有活性，表明它们可能是基于溶菌酶样化合物。最后，与这种抗菌活性相一致，我们发现，幼虫的存活率显着下降时，挑战溶菌酶耐药金黄色葡萄球菌，但不是挑战时，同一物种的溶菌酶敏感菌株。这些结果表明，Nicrophorus幼虫不是简单的被动接受来自父母的社会免疫，但他们是积极的参与者，在其生产。(C)2013年，动物行为研究协会。由爱思唯尔有限公司出版。保留所有权利。
Offspring of many animals develop in environments in which they are exposed to high densities of potentially harmful bacteria. For example, larvae of the carrion beetle Nicrophorus vespilloides face significant challenges from the bacteria they encounter during their development on decomposing vertebrate carcasses. We tested the idea that larvae secrete antimicrobial compounds during development to defend themselves against microbial exposure. We first showed that larval secretion of active antimicrobials peaked during the early stages of development. As has been found previously for parental secretions, larval secretions were active against Gram-positive but not Gram-negative bacteria, indicating that they might be based on lysozyme-like compounds. Finally, consistent with this antibacterial activity, we showed that larval survival declined significantly when challenged with lysozyme-resistant Staphylococcus aureus but not when challenged with a lysozyme-susceptible strain of the same species. These results demonstrate that Nicrophorus larvae are not simply passive recipients of social immunity derived from their parents, but that they are active participants in its production. (C) 2013 The Association for the Study of Animal Behaviour. Published by Elsevier Ltd. All rights reserved.