Internet-based cognitive behaviour therapy for obsessive-compulsive disorder: a randomized controlled trial.
Internet-based cognitive behaviour therapy for obsessive-compulsive disorder: a randomized controlled trial.
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DOI：
10.1017/s0033291712000244
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发表时间：
2012-10
影响因子：
6.9
通讯作者：
Ruck, C.
中科院分区：
文献类型：
--
作者：
Andersson, E.;Enander, J.;Andren, P.;Hedman, E.;Ljotsson, B.;Hursti, T.;Bergstrom, J.;Kaldo, V.;Lindefors, N.;Andersson, G.;Ruck, C.
认知行为疗法（CBT）是治疗强迫症（OCD）的有效方法，但CBT的使用机会有限。基于互联网的CBT（ICBT）与治疗师的支持可能是一个更容易获得的治疗。没有随机对照试验测试ICBT治疗强迫症。本研究的目的是探讨ICBT治疗强迫症的疗效在一项随机对照试验。被诊断为强迫症的参与者（n=101）被随机分配到10周的ICBT或注意力控制条件，包括在线支持治疗。主要的结果测量是耶鲁-布朗强迫症量表（YBOCS），由盲法评估者进行。两种治疗均导致强迫症症状的显著改善，但ICBT导致YBOCS的改善程度大于对照组，治疗后组间效应量（Cohen's d）为1.12（95% CI 0.69-1.53）。ICBT组显示临床显著改善的受试者比例为60%（95%CI 46-72），而对照组为6%（95%CI 1-17）。结果在随访时得到维持。ICBT是一种有效的治疗强迫症的方法，可以大大增加强迫症患者获得CBT的机会。重复研究是必要的。
Cognitive behaviour therapy (CBT) is an effective treatment for obsessive–compulsive disorder (OCD) but access to CBT is limited. Internet-based CBT (ICBT) with therapist support is potentially a more accessible treatment. There are no randomized controlled trials testing ICBT for OCD. The aim of this study was to investigate the efficacy of ICBT for OCD in a randomized controlled trial. Participants (n=101) diagnosed with OCD were randomized to either 10 weeks of ICBT or to an attention control condition, consisting of online supportive therapy. The primary outcome measure was the Yale–Brown Obsessive Compulsive Scale (YBOCS) administered by blinded assessors. Both treatments lead to significant improvements in OCD symptoms, but ICBT resulted in larger improvements than the control condition on the YBOCS, with a significant between-group effect size (Cohen's d) of 1.12 (95% CI 0.69–1.53) at post-treatment. The proportion of participants showing clinically significant improvement was 60% (95% CI 46–72) in the ICBT group compared to 6% (95% CI 1–17) in the control condition. The results were sustained at follow-up. ICBT is an efficacious treatment for OCD that could substantially increase access to CBT for OCD patients. Replication studies are warranted.