Discontinuation of nicotine replacement therapy among smoking-cessation attempters
Discontinuation of nicotine replacement therapy among smoking-cessation attempters
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DOI：
10.1016/j.amepre.2007.11.010
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发表时间：
2008-03-01
影响因子：
5.5
通讯作者：
Levinson, Arnold H.
中科院分区：
文献类型：
--
作者：
Burns, Emily K.;Levinson, Arnold H.
背景：尼古丁替代疗法（NRT）戒烟成功率加倍，但超过一半的NRT使用者不遵守最佳治疗方案。方法：从2005年科罗拉多州烟草调查中，分析2007年春季使用NRT戒烟企图者（N=366）。使用描述性和回归分析来检查停止NRT的原因，NRT的时间长度和戒烟意图。结果：停止NRT的原因是恢复吸烟（34%）、副作用（17%）、NRT对戒烟没有帮助（14%）、戒烟（10%）和费用（5%）。除戒烟外，贫困、年龄和非拉丁裔少数民族身份与戒烟原因有关。副作用与NRT使用时间短和下个月打算戒烟的几率降低95%有关。结论：在第一个人群水平的研究中，研究停止NRT的原因，在试图戒烟时开始使用NRT的普通人群吸烟者极有可能过早停止NRT。年龄和文化相适应的药物管理干预可能增加NRT的依从性并改善戒烟结果。
Background: Nicotine replacement therapy (NRT) doubles successful quitting, but more than half of NRT users do not comply with optimal treatment regimens.Methods: From the 2005 Colorado state tobacco survey, quit attempters who utilized NRT (N=366) were analyzed in spring 2007. Descriptive and regression analyses were used to examine reasons for discontinuing NRT, length of time on NRT, and quit intentions.Results: The reasons for discontinuing NRT were resuming smoking (34%), side effects (17%), NRT not helping with quitting (14%), quitting smoking (10%), and cost (5%). Poverty, age, and non-Latino minority status were associated with reasons for discontinuation other than quitting smoking. Having side effects was associated with a short duration of NRT use and 95% lower odds of intending to quit in the next month.Conclusions: In the first population-level study examining reasons for discontinuing NRT, general-population smokers who initiate NRT use when attempting to quit are highly likely to discontinue NRT prematurely. Age and culturally-appropriate medication management interventions may increase NRT compliance and improve cessation outcomes.