Age-specific prevalence of antibodies to hepatitis A and E viruses in Pune, India, 1982 and 1992.
Age-specific prevalence of antibodies to hepatitis A and E viruses in Pune, India, 1982 and 1992.
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1982 年和 1992 年印度浦那甲型肝炎和戊型肝炎病毒抗体的年龄特异性患病率。
DOI：
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发表时间：
1995
影响因子：
6.4
通讯作者：
R. Purcell
中科院分区：
文献类型：
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作者：
V. Arankalle;S. Tsarev;M. Chadha;D. Alling;S. Emerson;K. Banerjee;R. Purcell
对甲型肝炎病毒(HAV)和戊型肝炎病毒(HEV)抗体的年龄特异性血清阳性率在印度浦那进行了研究，这两种病毒都是地方病。数据显示，甲型肝炎病毒在3岁之前感染了大多数人，在儿童后期几乎100%感染。相比之下，HEV感染在儿童中很少见，直到成年早期才达到高峰流行(33%-40%)。甲型肝炎病毒和戊型肝炎病毒感染率不同的原因尚不清楚。相隔10年获得的血清样本的年龄特异性抗体模式表明，在这个印度社区，甲型肝炎病毒和戊型肝炎病毒在医学上的重要性都没有降低。
The age-specific seroprevalence of antibody to hepatitis A virus (HAV) and antibody to hepatitis E virus (HEV) were studied in persons in Pune, India, where both viruses are endemic. The data showed that HAV infected the majority of persons by age 3 years and virtually 100% by late childhood. In contrast, infection with HEV was rare in children and did not reach peak prevalence (33%-40%) until early adulthood. The reason for the differences in infection rates between HAV and HEV is not known. Age-specific antibody patterns in serum samples obtained 10 years apart show that neither HAV nor HEV has diminished in medical importance in this Indian community.